Java for Bioinformatics and Biomedical Applications - Bal, Hujol

The science and practice of medicine has undergone a fundamental change as a result of large-scale genome projects that led to the sequencing of a number of important microbial, plant and animal genomes in the last 5 years. This book aims to combine industry standard software engineering and design principles, genomics and bioinformatics and cancer research. It focuses on creating and integrating practical, useful tools for the scientific community in the context of real-life, real-value biomedical problems that researchers face on a routine basis, rather than being just a didactic exercise in learning a programming platform. The book leverages technologies for molecular biology, genomics and bioinformatics and cancer research developed by the NIH, NCI-Center for Bioinformatics (NCICB), the National Center for Biotechnology Information (NCBI, a division of the National Library of Medicine (NLM) at the NIH) and Stanford University.

Author: Harshawardhan Bal, Johnny Hujol
Paperback: 342 pages
Publisher: Springer; 1st Edition. edition (November 2, 2010)
Language: English
ISBN-10: 1441942459
ISBN-13: 978-1441942456

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Medical Infrared Imaging - Diakides, Bronzino

Rapid evolution of technical advances in infrared sensor technology, image processing, “smart” algorithms, databases, and system integration paves the way for new methods of research and use in medical infrared imaging. These breakthroughs permit easy-to-use, high-sensitivity imaging that can address key issues of diagnostic specificity and engender a new level of diagnostic standardization, thus enabling the even wider use of infrared imaging as a viable, non-invasive, lower-cost, safe and accessible first-line detection modality.

Edited by the inventor of the MedATR concept that leads to the first IR-CAD for the early detection of breast cancer, Medical Infrared Imaging presents many of the new ideas, concepts, and technologies that are key to the wider acceptance of infrared imaging as a revolutionary new standard. Beginning with the worldwide advances and their medical applications from a historical perspective, the book provides detailed and comprehensive information on the technology and hardware resulting from these innovative breakthroughs that will make currently contributory infrared information even more pertinent. The book covers the physics and physiological basis of thermal imaging, and such cutting-edge concepts as: dynamic thermal imaging, thermal tomography, the important role of infrared in a multi-modality imaging setting, and novel processing techniques for the early detection of breast cancer. A significant portion of the book introduces new applications such as biometric facial recognition and the clinical use and quantification of the TAU technique which uses functional imaging to determine the relevance, the stage, and the progression of diseases. Effective and reproducible results are crucial and the book emphasizes the importance of standardization, calibration, and protocols. Finally, the editor includes chapters on the use of databases for storage and retrieval of images and the ethical obligations of infrared research and clinical practice.

As a comprehensive state-of-the-science and indication of future directions, Medical Infrared Imaging provides the medical and biomedical engineering communities with the tools to fully utilize and further advance the applications of infrared imaging.

Author: Nicholas A. Diakides, Joseph D. Bronzino
Hardcover: 448 pages
Publisher: CRC Press; 1 edition (July 23, 2007)
Language: English
ISBN-10: 0849390273
ISBN-13: 978-0849390272

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Molecular and Cellular Signaling - Beckerman

The text is aimed at a broad audience of students and other individuals interested in furthering their understanding of how cells regulate and coordinate their core activities. Malfunction in the control layer is responsible for a host of human disorders ranging from neurological disorders to cancers. Most drugs target components in the control layer, and difficulties in drug design are intimately related to the architecture of the control layer. This book will be useful to students and individuals in medicine and pharmacology interested in broadening their understanding of how the control layer works. To further that goal, there are chapters on cancers and apoptosis, and on bacteria and viruses. In those chapters not specifically devoted to pathogens, connections between diseases, drugs and signaling are made.

The audience for this book includes students in chemistry, physics and computer science who intend to work in biological and medical physics, and bioinformatics and systems biology. The first five chapters of the book are mainly background and review chapters. Signaling in the immune, endocrine (hormonal) and nervous systems is covered along with cancer, apoptosis and gene regulation.

Author: Martin Beckerman
Paperback: 582 pages
Publisher: Springer; 1st Edition. edition (November 2, 2010)
Language: English
ISBN-10: 144191966X
ISBN-13: 978-1441919663

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Service Characteristics of Biomedical Material and Implants (Vol 3) - Batchelor, Chandrasekaran

A wide variety of materials is being used in biomedical engineering for various functions. This includes a range of ceramics, polymers and metallic materials for implants and medical devices. A major question is how these materials will perform inside the body, which is very sensitive to alien materials. The material must not only survive to perform its intended function but also not initiate any damage to the surrounding tissue or induce a wider health problem. The service characteristics of implanted materials are of vital concern to health treatments that alleviate ageing.

This book collates information and provides a concise text on the performance of different materials used in devices and implants. The knowledge presented is critical for a biomedical engineer, especially for the purpose of selecting the right materials. In addition, topics such as allergies and infection, tissue scaffolds, and drug delivery are reviewed.

Author: Andrew W. Batchelor, Margam Chandrasekaran
Hardcover: 242 pages
Publisher: Imperial College Press (December 2004)
Language: English
ISBN-10: 1860944752
ISBN-13: 978-1860944758

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Introductory Medical Imaging - Bharath

This book provides an introduction to the principles of several of the more widely used methods in medical imaging. Intended for engineering students, it provides a final-year undergraduate- or graduate-level introduction to several imaging modalities, including MRI, ultrasound, and X-Ray CT. The emphasis of the text is on mathematical models for imaging and image reconstruction physics. Emphasis is also given to sources of imaging artefacts. Such topics are usually not addressed across the different imaging modalities in one book, and this is a notable strength of the treatment given here. Table of Contents: Introduction / Diagnostic X-Ray Imaging / X-Ray CT / Ultrasonics / Pulse-Echo Ultrasonic Imaging / Doppler Velocimetry / An Introduction to MRI.

Author: A. A. Bharath
Paperback: 186 pages
Publisher: Morgan and Claypool Publishers; 1 edition (December 18, 2008)
Language: English
ISBN-10: 1598296116
ISBN-13: 978-1598296112

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Introduction to Biomedical Engineering, Biomechanics & Bioelectricity (Part 1) - Christensen

Intended as an introduction to the field of biomedical engineering, this book covers the topics of biomechanics (Part I) and bioelectricity (Part II). Each chapter emphasizes a fundamental principle or law, such as Darcy's Law, Poiseuille's Law, Hooke's Law, Starling's Law, levers, and work in the area of fluid, solid, and cardiovascular biomechanics. In addition, electrical laws and analysis tools are introduced, including Ohm's Law, Kirchhoff's Laws, Coulomb's Law, capacitors and the fluid/electrical analogy. Culminating the electrical portion are chapters covering Nernst and membrane potentials and Fourier transforms. Examples are solved throughout the book and problems with answers are given at the end of each chapter. A semester-long Major Project that models the human systemic cardiovascular system, utilizing both a Matlab numerical simulation and an electrical analog circuit, ties many of the book's concepts together. Table of Contents: Basic Concepts / Darcy's Law / Poiseuille's Law: Pressure-Driven Flow Through Tubes / Hooke's Law: Elasticity of Tissues and Compliant Vessels / Starling's Law of the Heart, Windkessel Elements and Volume / Euler's Method and First-Order Time Constants / Muscle, Leverage, Work, Energy and Power.

Author: Douglas A. Christensen
Paperback: 254 pages
Publisher: Morgan & Claypool Publishers; 1 edition (June 5, 2009)
Language: English
ISBN-10: 1598298445
ISBN-13: 978-1598298444

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